Efficient macrocyclisation of preorganized palindromic oligosquaramides
C. Rotger, M. N. Piña, M. Vega, P. Ballester, P. M. Deyà, A. Costa
Angew. Chem. Int. Ed. 2006, 45, 6844-6848
Abstract: Hydrogen-bonding interactions drive oligosquaramides of different lengths to fold into hairpin-like structures both in nonprotic and protic solvents. These compounds are useful preorganized precursors in macrocyclization reactions.