Transition metal-catalyzed hydrosilylation of carbonyl compounds and imines. A review
S. Díez-González, S. P. Nolan
Org. Prep. Proced. Int. 2007, 39, 523-559
Abstract: Reduction of carbonyl ans pseudo-carbonyl functions represents a ubiquitous protocol in organic synthesis. Transition metal catalysis has been successfully applied to the reduction of olefins, alkynes and many carbonyl compounds via hydrogenation or hydrosilylation. In contrat with hydrogenation, smooth reaction conditions are generally used in hydrosilylation reactions. Furthermore, this transformation can also be regarded as a useful method for the synthesis of different families of silicon-containing organic molecules. This review intends to provide a general overview of the possible applications of metal-catalyzed hydrosilylation of carbonyl compounds.