Primary and secondary aminophosphines as novel P-stereogenic building blocks for ligand synthesis
M. Revés, C. Ferrer, T. León, S. Doran, P. Etayo, A. Vidal-Ferran, A. Riera, X. Verdaguer
Angew. Chem. Int. Ed. 2010, 49, 9452-9455
Abstract: The reactivity of the amino group of P-stereogenic aminophosphines allows the further elaboration of the aminophosphine unit whilst preserving the original chirality of the phosphorus atom (see picture; Rh green). P-stereogenic aminodiphosphine ligands can easily be prepared in optically pure forms, feature distinct structural and electronic characteristics, and can be used in asymmetric hydrogenation reactions.